Large scale analysis solution must be able to provide very fast response time (<1sec) to some complex queries which are typically structured from a large fact table which is joined to many dimension tables and grouped-by them.

Using standard SQL databases such as MySQL InnoDB (as well as leading commercial vendors) will result in poor performance even when correct indexes are set up since in many case the database will be forced to perform unnecessary full table scans which will kill the performance if dimension tables are large.